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World commits to a pandemic response pact: what's next

Following a failure to rein in COVID, world leaders begin shaping an accord to prevent future disasters — one that holds them accountable. 

By Amy Maxmen01 December 2021

A video conference during a special session of World Health Assembly at the European Council building in Brussels.

Attendees of a special session of the World Health Assembly (virtual participants at the European Council shown here) decided to move forward with a new global accord on pandemic preparedness.Credit: François Walschaerts/AFP via Getty

As researchers scrambled this week to learn more about Omicron, the latest SARS-CoV-2 coronavirus variant of concern, world leaders met to negotiate a way of ensuring that a crisis on the scale of the COVID-19 pandemic never happens again. Initially on the table was a legally-binding pandemic treaty that would dictate how nations should respond to future outbreaks. A fuzzier form of that proposal is now moving forward, to be sharpened in the months and years to come.

“Omicron demonstrates just why the world needs a new accord on pandemics,” said Tedros Adhanom Ghebreyesus, director-general of the World Health Organization (WHO), at the start of the special session of the World Health Assembly, held 29 November to 1 December in Geneva. At the close of the meeting, he cited the need for a contract uniting countries, saying that it could curtail, “‘me-first’ approaches that stymie the global solidarity needed to deal with a global threat”.

International accords — or other treaty-adjacent frameworks — typically take years to become reality, and the process for this one is expected to continue until at least 2024. The pivotal decision by the WHO’s 194 member states at this assembly to move forward with a "new instrument" marks the first step. It stems from more than 200 recommendations made by five committees of researchers and policymakers who have dissected what has gone wrong in the COVID-19 pandemic.

“The failures have been colossal and systemic — we are living in a broken world,” says Stephen Morrison, director of global health policy at the Center for Strategic and International Studies in Washington DC. “What better a time to try to get something going that addresses the fundamental problems?”

Here, Nature explains the negotiations and the prospects for revamping global cooperation.

What was the outcome of the meeting?

After considering a wide range of recommendations for improving global pandemic response, attendees from the WHO’s member states decided to take several actions. One is to strengthen the WHO’s International Health Regulations (IHRs), a set of international laws designed to slow the spread of disease. One change that could be discussed next year is granting the WHO an ability to declare a pandemic (currently, it can only declare a Public Health Emergency of International Concern, which didn’t elicit a strong global response when it was announced for COVID-19).

European Council President Charles Michel gives a speech via video conference during a special session of World Health Assembly

European Council President Charles Michel pushed for a pandemic treaty to improve the world's response to outbreaks.Credit: François Walschaerts/AFP via Getty

But the biggest decision made at the assembly is to collectively develop an accord, agreement or other ‘new instrument’ to govern pandemic response, including ensuring the equitable distribution of diagnostics, drugs and vaccines. A measure outside of the IHRs is helpful, experts say, because those regulations do not oversee vaccines and other means of fighting pathogens.

The original proposal for such an ‘instrument’, driven largely by the president of the European Council, Charles Michel, contained toothy terms such as ‘legally binding’ and ‘treaty’, but they were notably absent from today’s announcement. Treaties tend to be legally binding such that a country not in compliance might be taken to international court.

What are the chances that an accord or other ‘instrument’ could still hold countries to account?

Many presidents and prime ministers ignored WHO recommendations regarding the COVID-19 pandemic and have not been held accountable for their actions, according to several analyses. For this reason, the European Council and Tedros, along with several countries, including Germany, France, and South Africa, have expressed their strong support for a legally binding pandemic treaty. But putting it — or another measure that holds countries accountable — in place would require adoption by two-thirds of the WHO’s 194 member states. Countries, including the United States and China, that are particularly defensive about their sovereignty, often oppose treaties, preferring terms such as ‘accord’ that can be interpreted differently, depending on the country. “If you’re more strict, you might get less buy-in,” explains Alexandra Phelan, a global health lawyer at Georgetown University in Washington DC.

Indeed, backing off of the more rigid terminology of ‘treaty’ seems to have drastically increased the number of countries willing to consider the proposal, with all 194 member states reaching a final consensus to move forward. In a statement released from the session, the head of US Health and Human Services, Xavier Becerra, said the United States wished to help shape a “new international instrument”. Becerra might have been influenced by the distressing reports of Omicron. “This past week’s news of a new variant of concern has heightened our antennae,” he said.

Kelley Lee, a global health policy researcher at Simon Fraser University in Burnaby, British Columbia, says that the future of this proposal will depend on its details, including which aspects of it are legally binding and how it is enforced. Wealthy countries are often eager to require nations to collect and openly report data, such as disease cases and genomic sequences from pathogens, she says. “There is a long-standing perception among many high-income countries that pandemics start ‘out there’ so they focus on early warnings,” she explains. However, these same countries might also push back on the enforcement of rules governing equitable access to vaccines and treatments because, as home to many pharmaceutical companies, they typically act to protect patent rights for economic self-interest, Lee says.

What might a pandemic pact entail?

The European Council’s Michel has said that a treaty would be a prime way to ensure the equitable distribution of vaccines and other medical countermeasures, such as protective equipment and diagnostic tests. Some researchers are scratching their heads about how a treaty, agreement or accord will accomplish this goal, in part because of the European Union’s opposition to waving intellectual-property rights for COVID-19 vaccines, a proposal made by South Africa and India that’s stalled because of a lack of consensus. A communications officer at the European Council says that a treaty would not be expected to focus on patent waivers, and “equitable access can be assured in many ways”.

One way to coax wealthy countries to share goods might be to link the action with sharing data, says Suerie Moon, a global health researcher at the Graduate Institute for International and Development Studies in Geneva. She and others point to the Pandemic Influenza Preparedness (PIP) Framework, created in 2006, as a model. This agreement arose in response to Indonesia withholding influenza samples after being denied access to flu vaccines that were developed on the basis of such viruses. Under PIP, countries agreed to share influenza samples so that pharmaceutical companies can make diagnostics, drugs and vaccines — and in return, companies have agreed to give a portion of those products to the WHO so that it can equitably distribute them to countries.

“With this type of deal, everybody gains something,” Moon says, but she adds that the negotiations are complicated because they involve multiple parties, including governments and pharmaceutical companies. Still, she says it’s worth trying. “This is the kind of issue that has gone unresolved at the global level, and it must be — to end this pandemic and prepare for the next one.”

When might the WHO adopt an accord or other ‘instrument’?

Revisions to the IHRs will probably be debated at the World Health Assembly meeting next May, and amendments might even be adopted by the end of next year. But a pandemic accord or other such tool will take at least another three years. At the end of the special session today, the WHO announced that an international group of health officials will now start hashing out the details. By 1 August, this group will have a draft of its proposal, including a term to describe what precisely the pact will be.

Health officials would then negotiate the terms for another year, and present it to countries for adoption at the World Health Assembly in May 2024. Countries that are unlikely to ratify a treaty, such as the United States, might still abide by it — if a treaty is the outcome, Phelan says. Like many onlookers, she hopes that the complexity of the issues and the plodding nature of the process does not stall action. “As someone looking at the future and dying to make a change, this has to be a pivotal moment,” she says.

doi: https://doi.org/10.1038/d41586-021-03596-y

(Sources: Nature)

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